Books /Synaptic Transmission and Plasticity Modulation in Nervous Systems

9781639899715

States Academic Press

English

2025

$ 156.95

Synaptic transmission is the process by which neurons communicate with each other through synapses, involving the release of neurotransmitters from the presynaptic neuron and their binding to receptors on the postsynaptic neuron. This process is fundamental to brain function, enabling the propagation of signals across neural networks. Plasticity modulation refers to the ability of synapses to strengthen or weaken over time, in response to increases or decreases in their activity. This synaptic plasticity is crucial for learning and memory formation. Long-term potentiation (LTP) and long-term depression (LTD) are key mechanisms of synaptic plasticity, where LTP enhances synaptic strength and LTD reduces it. Various factors, including neurotransmitter release frequency, receptor sensitivity, and intracellular signaling pathways, influence synaptic plasticity. Understanding these processes provides insights into the dynamic nature of neural circuits and their role in cognitive functions and neurodevelopmental and neurodegenerative disorders. Most of the topics introduced in this book cover new aspects of synaptic transmission and plasticity modulation in nervous systems. Such selected concepts that redefine this area have been presented in this book. Coherent flow of topics, student-friendly language and extensive use of examples make this book an invaluable source of knowledge.