9781639899463
Gabriel Murray
States Academic Press
English
2024
Medical Science - Immunology
$ 154
The innate immune system serves as the body's initial line of defense against pathogens, offering a rapid response to invading threats. Unlike the adaptive immune system, which tailors its response to specific pathogens, the innate system provides a generalized defense mechanism. Its components include physical barriers like the skin and mucous membranes, as well as cellular and molecular defenses such as phagocytes, natural killer cells, and antimicrobial proteins. Upon encountering pathogens, the innate immune system triggers inflammation, a process that recruits immune cells to the site of infection and enhances the elimination of invaders. Additionally, pattern recognition receptors (PRRs) on immune cells recognize conserved structures on pathogens, initiating the immune response. While the innate immune system lacks the specificity and memory of the adaptive immune system, its rapid and nonspecific nature enables it to provide immediate protection against a wide range of pathogens. This book is a compilation of chapters that discuss the most vital concepts and emerging trends in the field of innate immunity. The various advancements in this field are glanced at and their applications as well as ramifications are looked at in detail. This book on innate immunity is a collective contribution of a renowned group of international experts.